A female student， aged 18 years，w ho fell on her buttocks in a bicycle accident presents with swollen soft tissue， hot skin， and tenderness in the left buttock. The doctor suspects inflammation， where the patient has traumatic inflammation besides bacterial infection. Which of the following is NOT among the possible pathologic responses?
A. Vascular response
B. Infiltration of water， electrolyte，and plasma protein into the interstitial space
C. Entry of neutrophils and monocytes into the interstitial space
D. Increased arachidonic acid
E. Rupture and bleeding of blood vessels
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